Improvement of prediction of cardiovascular death by biomarkers.

CI = confidence interval; SD = standard deviation; WHtR = waist-to-height-ratio; HbA1c = hemoglobin A1c; IGF-1 = Insulin-like growth factor 1; hsCRP = high-sensitive C-reactive protein. Conventional cardiovascular risk factors include age, sex, systolic blood pressure, high-density lipoprotein cholesterol, total cholesterol, antihypertensive medication, diabetes, and current smoking.*For conventional risk factors only or conventional risk factors + biomarkers.†The bias-corrected accelerated bootstrap resampling procedure was used to calculate 95% confidence intervals.