*All cell lines were treated with increasing concentrations of Irvalec and cell growth inhibitory concentration (IC50) was determined after 72 h by MTT method. Values represent mean ± SD of three diff
Cell morphology features, such as those from the Cell Painting assay, can be generated at relatively low costs and represent versatile biological descriptors of a system and thereby compound response.
This study aimed to elucidate the radiobiological mechanisms of radium-223 dichloride ([223Ra]RaCl2)—an FDA-approved agent for metastatic castration-resistant prostate cancer—by investigating its in v
The IC50 of these compounds are significantly different (p<0.05) from each other in different magnitude (nM vs µM); while compounds with the same magnitude (nM vs nM and µM vs µM) are not significantl