The binding of thrombin or FPR-thrombin to immobilized γA/γA-fibrin, γA/γ′-fibrin, factor Va or GpIbα269-286ppp was quantified using SPR. Kd values for thrombin binding to γA/γA-fibrin and GpIbα269-28
Actin is an abundant protein that constitutes a main component of the eukaryotic cytoskeleton. Its polymerization and depolymerization are regulated by a variety of actin-binding proteins. Their funct
The association (ka) and dissociation (kd) rate constants, and the binding affinity (KD) are the average of three independent runs for each monoclonal antibody. For mAb 25B7/D7, 28E7/E4 and 14F6/A1 (1