Penicilindoles A–C, Cytotoxic Indole Diterpenes from the Mangrove-Derived Fungus <i>Eupenicillium</i> sp. HJ002
收藏NIAID Data Ecosystem2026-03-10 收录
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Three new indole diterpenes, penicilindoles A–C (1–3), were isolated from the mangrove-derived fungus Eupenicillium sp. HJ002. Their planar structures and absolute configurations were determined by interpretation of NMR spectroscopic data, HR-ESIMS, and X-ray diffraction analysis using Cu Kα radiation. The cytotoxic and antibacterial activities were evaluated in vitro; penicilindole A (1) showed cytotoxic activity against human A549 and HepG2 cell lines with IC50 values of 5.5 and 1.5 μM, respectively.
创建时间：
2018-02-28
