Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-N'-(5-fluoro-3H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1717)

Protein Data Bank Japan2024-11-13 更新2026-03-21 收录

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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-N'-(5-fluoro-3H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1717) Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, METHIONINE, ... Authors: Koh, C.-Y, Hol, W.G.J. Deposit date: 2015-05-14 Release date: 2016-05-04 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors. Acs Infect Dis., 2, 2016

创建时间：

2015-05-14