遇见数据集

RNAseq functional analysis of SMA model in C. elegans at the L4 stage

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NIAID Data Ecosystem2026-05-10 收录
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This dataset comprises RNA sequencing and downstream functional analyses of Caenorhabditis elegans models of spinal muscular atrophy (SMA). Samples were collected at the early L4 larval stage from wildtype and smn-1 mutant strains to assess gene expression changes associated with SMA phenotype onset. The submitted data include processed tables for gene ontology enrichment, alternative splicing events, and differential gene expression analyses performed to characterize molecular pathways impacted by smn-1 deficiency. Raw reads for all samples are available in ENA under the provided accession numbers. This dataset supports the findings published in the corresponding manuscript describing SMA pathomechanisms using C. elegans as a model organism.

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2025-11-17
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