Genome-wide maps of MRE11, NBS1 total RNAPII and phospho-Ser2-RNAPII in WT cells, upon shControl, shMRE11 or shNBS1 treatment, after treatment by DRB and after heat shock in HeLa cells

we used the technnology of ChIP-sequencing to sepcifically analyze the recruitment of the MRN Complex onto target genes in conjunction with RNAPII, investigating the effect of the depletion of MRN complex on RNAPII and active transcription HeLa were treated with shRNA or with DRB, or were heatshocked, and the different factors were ChIPed