Bulk RNA-sequencing of microglia in 3XTg-AD mice treated with anti-Nk1.1 depleting antibodies or isotype control
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https://www.ncbi.nlm.nih.gov/sra/SRP239328
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The goal of this experiment is to determine the effects of NK cells on microglia inflammation in 3XTg-AD mice. We examined the transcriptomal changes of microglia in mice treated with anti-NK1.1 anitbodies and isotype controls by deep RNA-Seq. Overall design: We depleted NK cells in 3XTg-AD mice using anti-NK1.1 depleting antibodies. We then sorted microglia by flouorescence activated cell sorting. RNA-seq was performed with the bulk microglia populations.
创建时间:
2020-06-09



