首页/数据集/TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

NIAID Data Ecosystem2026-05-01 收录

乳腺癌表观遗传学

雌激素受体信号

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE236176 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2024-03-24

乳腺癌表观遗传学

激素基因调控

Abstract: The use of mouse derived mammary organoids can provide a unique strategy to study mammary gland development through a normal life cycle, as well as offering insights into how malignancies fo

NIAID Data Ecosystem80

Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance

乳腺癌表观遗传学

染色质三维结构动态

To establish a data-driven learning model of the temporal dynamics and 3D chromatin reorganization, we conducted tethered chromatin conformation (TCC) sequencing to examine 3D structure dynamics in es

NIAID Data Ecosystem50

Gene Regulation by Estrogen Signaling and DNA Methylation in MCF7 Breast Cancer Cells

乳腺癌表观遗传学

激素信号通路

Estrogen signaling and epigenetic modifications, in particular DNA methylation, are involved in regulation of gene expression in breast cancers. Here we investigated a potential regulatory cross-talk

NIAID Data Ecosystem50

Reduction N6AMT1-mediated 6mA DNA modification promotes tumor progression [MeDIP-seq]

乳腺癌表观遗传学

DNA6mA甲基化分析

Background: DNA N6-methyladenosine (6mA) as a novel epigenetic signaling modification in humans and has been implicated in progression and tumorigenesis of several cancers. However, the function and m

NIAID Data Ecosystem60

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as potential diagnostic markers for breast cancer

乳腺癌表观遗传学

游离DNA生物标志物

Breast cancer is one of the most prevalent cancers among women, and early diagnosis is crucial in reducing the mortality rate. This study aims to identify novel, reliable, and specific biomarkers for

DataCite Commons2025-05-15 更新50

TRPS1 modulates chromatin accessibility to regulate estrogen receptor (ER) binding and ER target gene expression in luminal breast cancer cells

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