Parameters used in the simulations of epithelial polarization.

We have simulated Model (1–8) with parameter values compatible with the interactions described in Fig. 10 for the process of epithelial polarization. At initial time the plasmamembrane is in a uniform PIP3-rich state. We then create a circular patch of the PIP2-rich phase of radius and investigate its dynamics to check whether a stable polarization state is attained.