Longitudinal gene expression profiling of self-collected blood samples in COVID-19+ and healthy participants. Longitudinal gene expression profiling of self-collected blood samples in COVID-19+ and healthy participants

Longitudinal cohort: 773 host response genes were profiled in previously vaccinated (n=16) and unvaccinated (n=14) COVID-19+ participants along with 5 healthy uninfected controls across a 2-week observational window Single timepoint cohort: 773 host response genes were profiled in 6 healthy uninfected participants Overall design: Longitudinal cohort: 30 COVID-19+ and 5 uninfected participants were asked perform self-collection and stabilization of capillary blood using a novel technology (homeRNA) every other day for two weeks (7 longtiudinal timepoints per participant). Temporal kinetics of 773 immune genes were profiled using the nCounter direct digital counting of native mRNA. Single timepoint cohort: 6 healthy uninfected participants were asked perform self-collection and stabilization of capillary blood using a novel technology (homeRNA). Temporal kinetics of 773 immune genes were profiled using the nCounter direct digital counting of native mRNA.