Protein-Protein Interaction network properties of disease genes.

Data for PPI networks for disease lethal (DL), disease viable (DV), lethal (L), viable (V) and disease unknown (DU) genes. “Proteins” represent the sum of proteins in a given group (DL, DV, L, V or DU) and their interacting partners (from any group). Statistical analysis was performed for all interactions (e.g. proteins of the same classification and proteins of different classifications). The total number of PPIs are indicated under “Interactions” and the number of PPIs for the most highly connected protein is indicated under “MaxDegree”. “Average Degree” corresponds to the mean number of PPIs for all interacting proteins. “Comps” designates the number of independent groups (components) of interactions, the largest of which comprises the “Largest Connected Component”. The percentages of proteins and interactions, and the average degree found within the largest connected component are given.