Fbxo7

ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein kinase binding (ortholog); ubiquitin binding (ortholog); INVOLVED IN negative regulation of neuron apoptotic process; positive regulation of mitophagy; autophagy of mitochondrion (ortholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH genetic disease (ortholog); glucose-galactose malabsorption (ortholog); muscular dystrophy-dystroglycanopathy type B6 (ortholog); FOUND IN classical Lewy body (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A

编码一种具有蛋白质异二聚化活性（同源物）、蛋白激酶结合（同源物）、泛素结合（同源物）的蛋白质；参与神经元凋亡过程的负调节、线粒体自噬的正调节、线粒体自噬（同源物）；参与帕金森病通路；与遗传疾病（同源物）相关；涉及葡萄糖-半乳糖吸收不良（同源物）、肌营养不良-营养不良性肌病B6型（同源物）；存在于经典路易体（同源物）、细胞质（同源物）、细胞溶质（同源物）；与2,3,7,8-四氯二苯并-对-二噁英、4,4'-磺酰二苯酚、双酚A相互作用。