Chiral Monodentate Trialkylphosphines Based on the Phospholane Architecture
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https://figshare.com/articles/dataset/Chiral_Monodentate_Trialkylphosphines_Based_on_the_Phospholane_Architecture/2461765
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资源简介：
The development of efficient chiral monodentate phosphine
ligands lags behind that of the bidentate congeners. This holds especially
true for highly electron rich chiral phosphine analogues able to replace
the ubiquitous tricyclohexylphosphine and tri-tert-butylphosphine in catalytic asymmetric transformations. We present
a convenient and modular synthesis of a set of chiral monodentate
ligands with different steric demands based on the popular phospholane
scaffold. Their steric and electronic properties were determined by
their corresponding nickel and palladium complexes. They represent
good mimics of the popular tricyclohexylphosphine and tri-tert-butylphosphine ligands. Their potential was subsequently
evaluated in palladium-catalyzed asymmetric C(sp3)–H
functionalization leading to indolines.
创建时间：
2012-12-10
