File S1 - Methylation of Migraine-Related Genes in Different Tissues of the Rat

Figure S1. Example of standard curve, showing the distribution of methylation of the known samples for the Esr1 gene. Table S1. Body weight (g) and bodyweight changes (Δ, g) in rats after different treatments (n = 11–14). * p<0.05 compared to OVX placebo. Differences were calculated using one-way ANOVA. Table S2. Estradiol and CGRP concentrations measured at day 1, day 7 and day 21 and progesterone concentrations measured at day 21. * p<0.05 compared to both sham and OVX animals treated with placebo pellet. Differences were calculated using one-way ANOVA. (DOCX)