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Deregulation of neuro-developmental genes and primary cilium cytoskeleton anomalies in iPSC retinal sheets from human syndromic ciliopathies

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE133247
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We generated iPSCs from control and ciliopathy cases and differentiated them into polarized 3D-adherent retinal sheets that could recapitulate normal photoreceptor development and disease state, respectively. Retinal sheets mRNA profiles at dau 60 of differentiation from 4 Ctrl, 2 MKS and 1 BBS patient in duplicate, using Ion Torrent platform.
创建时间:
2020-03-23
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