Crystal structure of BRD9 bromodomain in complex with a valerolactam quinolone ligand
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Crystal structure of BRD9 bromodomain in complex with a valerolactam quinolone ligand Descriptor: 1,4-dimethyl-7-(2-oxopiperidin-1-yl)quinolin-2(1H)-one, Bromodomain-containing protein 9 Authors: Tallant, C, Structural Genomics Consortium (SGC), Clark, P.G.K, Vieira, L.C.C, Krojer, T, Nunez-Alonso, G, Picaud, S, Fedorov, O, Dixon, D.J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brennan, P.E, Knapp, S. Deposit date: 2015-04-05 Release date: 2015-05-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Angew.Chem.Int.Ed.Engl., 54, 2015
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2015-04-05
