Freq = frequency of allele 2 in unaffected BRCA1 carriers.HR = Per allele Hazard Ratio associated with allele 2, under a single disease risk model, unless specified.r2: correlation between the SNP in
We obtained peripheral blood samples for women from Utah (USA) and Ontario (Canada) who had a family history of breast cancer (or did not), who carried a BRCA1/2 mutation (or did not), and who had dev
This dataset consists of miRNA expression in plasma of 78 women with germline BRCA1/2 mutations and expression in serum of 11 of them. Serum samples of remaining 67 women have been already submitted t
“AD Risk” is the predictive ability of PRS derived from Schwartzentruber et al. 2021. “Progression” is the predictive ability of PRS derived from the progression GWAS reported here; ie, the GSK GWAS i