In vivo molecular imaging with target-specific activatable “smart” probes, which yield fluorescence only at the intended target, enables sensitive and specific cancer detection. Dimerization and fluor
A covalently triggered fluorescence turn-on detection scheme has been implemented for a tris(N-salicylideneamine)-derived dynamic fluorophore. Selective cleavage of strategically placed Si−O bonds by
We present a computational protocol for the fast and automated screening of excited-state hybrid quantum mechanics/molecular mechanics (QM/MM) models of rhodopsins to be used as fluorescent probes bas
