The occurrence of a previously unknown neuroaxonal dystrophy (NAD) has been noticed in Perro de Agua Español (Spanish water dogs). Clinically, affected dogs displayed weakness of the pelvic limbs and
Purpose: The advancements in the next-generation sequencing (NGS) techniques have allowed for rapid, efficient, and cost-time-effective genetic variant detection. However, in both clinical practice an
Introduction Both late-onset Alzheimer’s disease (AD) and ageing have a strong genetic component. In each case, many associated variants have been discovered, but how much missing heritability remains
