Epigenetic processes including RNA methylation, post-translational modifications, and non-coding RNA expression have been associated with the heritable risks of systemic lupus erythematosus (SLE). In

NIAID Data Ecosystem20

Groups of IgG N-glycans from Table 3 that showed statistically significant difference in observed values (corrected by sex, age, and African admixture) between 101 Afro-Caribbean cases with SLE and 183 controls.

肿瘤糖基化组学

系统性红斑狼疮

*t-test for equality of means (2-tailed).

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Evaluation of global methylation profile in recipient BMMSCs of MRL/lpr mice after cell therapy (MeDip). Mus musculus

表观遗传治疗

系统性红斑狼疮

Mesenchymal stem cell transplantation (MSCT) has been widely used to treat a variety of human diseases. However, the detailed mechanisms underlying its success are not fully understood. Here we show t

NIAID Data Ecosystem30

DataSheet_1_The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus.docx

系统性红斑狼疮

额外滤泡B细胞反应

IntroductionMany autoimmune diseases are characterized by germinal center (GC)-derived, affinity-matured, class-switched autoantibodies, and strategies to block GC formation and progression are curren

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