StE(z)2, a polycomb group methyltransferase and deposition of H3K27me3 and H3K4me3 regulate the expression of tuberization genes in potato

In this work, we investigated the role of a PRC2 group H3K27 methyltransferase StE(z)2 in the photoperiod-dependent tuberization phenomenon in potato (S. tuberosum ssp. andigena). In order to identify the direct targets of StE(z)2 as well as genes associated with H3K4me3 and H3K27me3 modifications during tuberization, we have performed chromatin immunoprecipitation sequencing (ChIP-seq) on SD-induced stolons from wild-type and FLAG-tagged StE(z)2-OE line. This investigation showed that two histone modifications (H3K27me3 and H3K4me3) regulate the expression of key tuberization genes in potato.