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X-RAY structure of PHDvC5HCH tandem domain of NSD2

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Protein Data Bank Japan2025-01-22 更新2026-04-19 收录
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X-RAY structure of PHDvC5HCH tandem domain of NSD2 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Histone-lysine N-methyltransferase NSD2, ... Authors: Musco, G, Cocomazzi, P, Berardi, A, Knapp, S, Kramer, A. Deposit date: 2024-07-31 Release date: 2024-12-18 Last modified: 2025-01-22 Method: X-RAY DIFFRACTION (1.76 Å) Cite: The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma. Nucleic Acids Res., 53, 2025

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2024-07-31
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