AEBSF sites on HAS.

T-test: Lists t-test results between RA and non-RA subjects, as well HPR and LPR subjects, showing significance between RA and non-RA subjects in each comparison. The average intensity of the sum of all of AEBSF modification sites on HSA of each sample, for RA and non-RA, as well as HPR and LPR, is shown. A t-test was also performed between groups for modification sites in clusters 1, 2, and 3.AEBSF_HSA (site): This dataset lists the structure characteristic of the 41 AEBSF sites on HSA, including association with the cluster groups from Fig 5B, HC order from Inferno, site position from Uniprot, site position from PDB ID 1N5U, HSA domain, HSA subdomain, amino acid (AA), secondary structure (SS), surface accessible surface area (SASA) score, number of peptides used for the quantification of the site, peptide sequence, and the intensity from each sample. (The intensity here used the area from S3 Data. Only peptides from HSA and with AEBSF modifications are retained. The area of peptides that have same AEBSF modification site are combined (the number of peptides is used for combination is listed in column #peptide combined). After consolidation, site that have less than 12 hits are removed. Note that the sequence/start/end for sites that used more than 1 peptides are just representative. The intensity is also used for Inferno analysis).AEBSF_HSA_(cluster site): A list of all samples, with their groups (RA/non-RA and HPR/LPR), as well as the intensity sum of AEBSF modification for each modification site in cluster C1, C2, C3 on HSA. T-test: Lists t-test results between RA and non-RA subjects, as well HPR and LPR subjects, showing significance between RA and non-RA subjects in each comparison. The average intensity of the sum of all of AEBSF modification sites on HSA of each sample, for RA and non-RA, as well as HPR and LPR, is shown. A t-test was also performed between groups for modification sites in clusters 1, 2, and 3. AEBSF_HSA (site): This dataset lists the structure characteristic of the 41 AEBSF sites on HSA, including association with the cluster groups from Fig 5B, HC order from Inferno, site position from Uniprot, site position from PDB ID 1N5U, HSA domain, HSA subdomain, amino acid (AA), secondary structure (SS), surface accessible surface area (SASA) score, number of peptides used for the quantification of the site, peptide sequence, and the intensity from each sample. (The intensity here used the area from S3 Data. Only peptides from HSA and with AEBSF modifications are retained. The area of peptides that have same AEBSF modification site are combined (the number of peptides is used for combination is listed in column #peptide combined). After consolidation, site that have less than 12 hits are removed. Note that the sequence/start/end for sites that used more than 1 peptides are just representative. The intensity is also used for Inferno analysis). AEBSF_HSA_(cluster site): A list of all samples, with their groups (RA/non-RA and HPR/LPR), as well as the intensity sum of AEBSF modification for each modification site in cluster C1, C2, C3 on HSA. (XLSX)