Clinical and histological characteristics of prostate cancer patients with bone metastases and treated with metastasis surgery.

Continuous values are given as median (min-max values).aCastration-resistant patients had disease progression after long-term androgen deprivation therapy including surgical ablation, LHRH/GNRH agonist therapy, and therapy with anti-androgen (bicalutamide).bRadiation towards operation site.cThe time between date of surgery and the latest follow-up examination or death.dAndrogen receptor (AR) and prostate specific antigen (PSA) immunohistochemical staining scores were assessed according to details described in the materials and methods section.eProliferation indexes were assessed as fractions of proliferating (Ki67 immunostained) tumor epithelial cell, according to details described in the materials and methods section.