Supplementary Table 4 from Activating Inducible T-cell Costimulator Yields Antitumor Activity Alone and in Combination with Anti-PD-1 Checkpoint Blockade
RNA-Sequencing of humanized mice bearing subcutaneous pancreatic tumors expressing either Ctrl shRNA or SDR16C5 shRNA received control PBS or PD-1 treatment.
This study investigates signaling responses in wild-type (WT) Jurkat cells and engineered OSA-Jurkat cells (M2 and M7 types) under basal and activated conditions.
It is now widely known that C-X3-C motif ligand 1 (CX3CL1) plays an essential part in the process of regulating pro-inflammatory cells migration across a wide range of inflammatory disorders, includin
Recombinant cytokines have limited anti-cancer efficacy mostly due to narrow therapeutic window and systemic adverse effects. IL-18 is an inflammasome induced proinflammatory cytokine that enhances T