Tissue resident macrophages show their specific function to maintain homeostasis in our body. Dysfunction of alveolar macrophages (AMs), which regulate the proper amount of surfactant protein, leads t
Gene regulation upon serotonin stimulation was compared in wild-type and 5HT2C receptor kock-out mice. Serotonin (5-HT), known as neuromodulator, regulates immune responses and inflammatory cascades.
In our lower respiratory tract, the alveolar spaces are divided from the bloodstream and the external environment by only a few microns of interstitial tissue. Alveolar macrophages (AMs) defend this d
Purpose: To identify IgE inhibitory bioactive compound from A.Lappa for targeted therapy on peanut specific IgE production and hypersensitivity reactions, and to investigate its underlying mechanisms.
Pulmonary arterial hypertension (PAH) is a subgroup of pulmonary hypertension characterized by progressive elevation of pulmonary arterial resistance due to vascular remodeling and right-heart failure
