Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor

Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor Descriptor: 3-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}-N-(pyridin-2-ylmethyl)propanamide, Hepatocyte growth factor receptor Authors: Soisson, S.M, Rickert, K.W, Patel, S.B, Lumb, K.J. Deposit date: 2011-01-03 Release date: 2011-01-19 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis for selective small molecule kinase inhibition of activated c-Met. J.Biol.Chem., 286, 2011