Genetic associations between gut microbiota and type 2 diabetes mediated by plasma metabolites

Table 1 Instrumental variables of gut microbiota after clumping and exclusion of week IVsTable 2 Instrumental variables of plasma metabolites after clumping and exclusion of week IVsTable 3 Genetic correlation between gut microbiota and type 2 diabetes (LDSC analysis)Table 4 Causal effects of gut microtiota on type 2 diabetes (Forward MR analysis)Table 5 Causal effects of type 2 diabetes on gut microbiota (Reverse MR analysis)Table 6 Causal assciations between plasma metabolites and type 2 diabetes (Associations only with PIVW less than 0.05 and consistent with all sensitivity analysis were listed)Table 7 Causal assciations between gut microbiota and 109 plasma metabolitesTable 8 Mediantion analysis between gut microbiota, plasma metabolites, and type 2 diabetes