Summary of genomic and exonic coverage in the twenty sequenced genomes.

Coverage was defined as the percentage of bases in the genome/exome that have at least 5 reads with a Phred-like consensus score of greater than zero at that position. The total size for the autosomal genome is 2,681,301,098 bp, which is the total reference length of the autosomes (NCBI human genome assembly build 36) minus the reference sequence gaps (‘N’ calls in reference sequence). The total size for the autosomal exons is 65,471,109 bp, which is the total length of the autosomal exons, defined as all protein coding gene entries in Ensembl core database version 50 [13]. The Ensembl database version 50 is based on the NCBI human genome assembly build 36 as well as its annotations (GeneBank).