The University of California San Francisco Preoperative Diffuse Glioma MRI (UCSF-PDGM)

The publicly available University of California San Francisco Preoperative Diffuse Glioma MRI (UCSF-PDGM) dataset consists of 501 patients with histopathologically-proven World Health Organization (WHO) grade 2-4 diffuse gliomas who were imaged with a standardized 3T preoperative brain tumor MRI protocol featuring predominantly three-dimensional (3D) imaging and including advanced imaging techniques such as high angular resolution diffusion imaging and arterial spin labeling perfusion imaging. The dataset also includes isocitrate dehydrogenase (IDH) mutation status for all patients and O[6]-methylguanine-DNA methyltransferase (MGMT) promotor methylation status for patients with WHO grade 3 and 4 gliomas. Basic clinical details are also provided, including extent of resection and overall survival. The UCSF-PDGM adds to on an existing body of publicly available diffuse glioma MRI datasets that can be used in image-based brain tumor research.

公开可用的加州大学旧金山分校术前弥漫性胶质瘤磁共振成像（UCSF-PDGM）数据集，包含501例经组织病理学证实的世界卫生组织（WHO）2~4级弥漫性胶质瘤患者。所有患者均采用标准化3T术前脑肿瘤磁共振成像方案扫描，该方案以三维（3D）成像为主，同时涵盖高角度分辨率扩散成像、动脉自旋标记灌注成像等先进成像技术。本数据集还收录了所有患者的异柠檬酸脱氢酶（isocitrate dehydrogenase, IDH）突变状态，以及WHO 3级和4级胶质瘤患者的O6-甲基鸟嘌呤-DNA甲基转移酶（O[6]-methylguanine-DNA methyltransferase, MGMT）启动子甲基化状态。此外还提供了患者的基本临床信息，包括手术切除范围与总生存期。UCSF-PDGM数据集丰富了现有的公开可用弥漫性胶质瘤磁共振成像数据集资源，可应用于基于影像的脑肿瘤研究。