Circulating monocytes and cardiac macrophages in diastolic dysfunction
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Toll-like receptor signaling pathway
Specific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors ide
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NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence
The uppermost part of the pathway includes part of the general NAM salvage pathway in the cytosol as it is relevant to senescence-induced changes to NAD metabolism. In this pathway, NAD levels are mai
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Eicosanoid metabolism via cyclooxygenases (COX)
This pathway is inspired by the Lipidmaps>Eicosanoids Pathway expended pathway display [https://lipidmaps.org/pathway/pathways_maps] and extended with the top left side of Figure 1 from Dennis and Nor
wikipathways.github.io100
p53 pathway
p53 (also known as protein 53 or tumor protein 53), is a transcription factor which in humans is encoded by the TP53 gene. p53 is important in multicellular organisms, where it regulates the cell cycl
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Estrogen metabolism
Estrogens are metabolized via hydroxylation by cytochrome P450 enzymes such as CYP1A1 and CYP3A4 and via conjugation by estrogen sulfotransferases (sulfation) and UDP-glucuronyltransferases (glucuroni
wikipathways.github.io100
