Circulating monocytes and cardiac macrophages in diastolic dysfunction
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Primary focal segmental glomerulosclerosis (FSGS)
Primary or idiopathic focal segmental glomerulosclerosis (FSGS) a cause of nephrotic syndrome in children and adolescents, as well as an important cause of end stage renal disease in adults. FSGS is m
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Deregulation of Rab and Rab effector genes in bladder cancer
Example of the Rab27 cluster. The Rab27 cluster is comprised of the two RAB27 isoforms (RAB27A and RAB27B), the GEF MADD, the GAP TBC1D10A and 12 effector proteins
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Asparagine degradation
Like many other amino acids, asparagine may be utilized by S. cerevisiae as a sole source of nitrogen. Catabolism of asparagine for nitrogen involves the action of asparaginases, which hydrolyze the a
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Glucocorticoid receptor pathway
The glucocorticoid receptor (GR, a.k.a. NR3C1) is a nuclear receptor that is activated upon binding of cortisol or glucocorticoids. It mainly regulates gene expression of several groups of genes in tw
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Ovarian infertility
Ovarian bottleneck genes associated with infertility. A valuable approach to the study of infertility is the comparison of mutations of individual human and mouse genes associated with infertility phe
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