P.gingivalis-LPS differentially suppresses M1 & M2 Mφ cytokines.

Endotoxin tolerisation effects on PG-LPS-induced suppression of TNFα, IL-6 and IL-10 secretion by THP-1-derived M1 and M2 Mφ subsets, where data is presented as % reduction of, or % increase over PG-LPS stimulus controls. Cytokine reduction is indicated by a downwards pointing arrow, whereas augmentation of LPS-induced cytokines are indicated by an upwards pointing arrow. Data presented is representative of n = 3 replicate experiments, already published in [5] and serves as a comparator with E. coli K12-LPS induced ET presented in Fig 3.