five

Dibenzooxepinone inhibitor 12b in complex with p38 MAPK

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Dibenzooxepinone inhibitor 12b in complex with p38 MAPK Descriptor: 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{N}-(2-morpholin-4-ylethyl)-11-oxidanylidene-6~{H}-benzo[c][1]benzoxepine-9-carboxamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside Authors: Buehrmann, M, Rauh, D. Deposit date: 2017-01-11 Release date: 2017-09-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Design, Synthesis, and Biological Evaluation of Novel Type I(1)/2 p38 alpha MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine. J. Med. Chem., 60, 2017
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2017-01-11
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