Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control
Ratios to melanocytes are presented for the % of methylation in melanoma cell lines and melanocytes (MM/mel) and the fresh-frozen tumors (FT/mel). MM malignant melanoma. mel melanocytes. FT fresh-froz
Additional file 7: Table S6. Number of paternally provided Chromatin remodeler cofactors, RNA interactors, readers, erasers and writers (CRREWs). A) Number of paternally provided CRREWs. B) Number of
For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e