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Mutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2)

ChEBI2021-03-05 更新2026-07-12 收录

ALS疾病模型

神经细胞转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-10104 数据链接链接失效反馈

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Mutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2)

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创建时间：

2021-03-05

神经元研究

ALS疾病模型

Oculomotor neurons, which regulate eye movement, are resilient to degeneration in the lethal motor neuron disease amyotrophic lateral sclerosis (ALS). It would be highly advantageous if motor neuron r

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Hippocampal neurons’ cytosolic and membrane-bound ribosomal transcript profiles are differentially regulated by learning and subsequent sleep

记忆巩固机制

神经细胞转录组学

The hippocampus is essential for consolidating transient experiences into long-lasting memories. Memory consolidation is facilitated by postlearning sleep, although the underlying cellular mechanisms

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In Vivo Imaging Reveals Distinct Inflammatory Activity of CNS Microglia versus PNS Macrophages in a Mouse Model for ALS

ALS疾病模型

神经炎症成像

Mutations in the enzyme superoxide dismutase-1 (SOD1) cause hereditary variants of the fatal motor neuronal disease Amyotrophic lateral sclerosis (ALS). Pathophysiology of the disease is non-cell-auto

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Control_vs_Stress_P50_VisualCortex_annotated_results.txt

神经细胞转录组学

视觉皮层发育

Transcriptomic data examining impact of early-life stress on visual cortex mRNA expression.

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Conserved role for spliceosomal component PRPF40A in microexon splicing. Conserved role for spliceosomal component PRPF40A in microexon splicing

外显子剪接分析

神经细胞转录组学

Microexons (exons ≤30 nts) are important features of neuronal transcriptomes, but pose mechanistic challenges to the splicing machinery. We previously showed that PRP-40, a component of the U1 spliceo

NIAID Data Ecosystem60

Mutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2)

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