Forward and reverse designs using IPRO with specified positions for mutations.
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aThe starting X-ray structures used for IPRO designs. GL in the parentheses indicate the structure is germline and AM is for affinity maturation.bThe number of mutations identified by comparing GL and AM antibody sequences.cInteraction energy between an antigen and an antibody. All energies are in kcal/mol.dThe IE difference calculated from AM - GL.
创建时间：
2015-12-02
