EGFR (T79M/V948R) in complex with naquotinib and an allosteric inhibitor
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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EGFR (T79M/V948R) in complex with naquotinib and an allosteric inhibitor Descriptor: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide, 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-2-carboxamide, Epidermal growth factor receptor Authors: Beyett, T.S, Eck, M.J. Deposit date: 2021-01-19 Release date: 2022-02-23 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors. Nat Commun, 13, 2022
创建时间：
2021-01-19
