Relationship between dog tissue L. infantum loads, time since infection, anti-Leishmania IgG, clinical status, and infectiousness.

Coefficients expressed as incidence rate ratios. Data fitted to random effects negative binomial regression models, with time since infection as a covariate.1Model includes ln bone marrow parasite number as a covariate.2Infectiousness to sandflies measured by xenodiagnosis.3Dogs were classified according to their total clinical score as asymptomatic (scores 0–2), oligosymptomatic (3–6) and symptomatic (>6) at each bimonthly examination.