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Cryo-EM structure of the cytosol AhR complex

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https://www.omicsdi.org/dataset/jpost/PXD038120
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Aryl hydrocarbon receptor (AhR) is an important ligand-activated transcription factor involved in the regulation of various important physiological functions. AhR can be activated by a variety of signals with different affinities, including xenobiotics and endogenous signals. In the absence of ligand, AhR forms a stable multiprotein complex in the cytosol with the chaperone Hsp90 and co-chaperon p23, XAP2.
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2022-12-26
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