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NOTCH1 Drives Sexually Dimorphic Immune Responses in Hepatocellular Carcinoma

NIAID Data Ecosystem2026-05-02 收录

肿瘤免疫学

肝细胞癌性别差异

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218377 数据链接链接失效反馈

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资源简介：

We study the role of NOTCH1 in immune escape in HCC. Examination of transcriptional profiles in NOTCH1 murine tumors

应用场景：

创建时间：

2025-02-07

肿瘤免疫学

T细胞耗竭

We aimed to investigate the association between HPK1 expression and exhausted status of tumor. Overall design: Bulk RNA-seq was performed on fresh-frozen tissue samples of renal cell carcinoma.

NIAID Data Ecosystem60

Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice

肿瘤免疫学

肿瘤浸润淋巴细胞

CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie

NIAID Data Ecosystem60

Sema4D correlates with tumour immune infiltration and is a prognostic biomarker in bladder cancer, renal clear cell carcinoma, melanoma and thymoma

肿瘤免疫学

生物标志物

Sema4D, a member of the immune semaphorin family, plays crucial roles in the immune regulation, bone resorption and nervous system. It is also involved in angiogenesis and tumour progression. However,

DataCite Commons2024-02-23 更新50

肿瘤免疫学

基因调控

Genes related to immune suppression that are negatively regulated by DMHCA in tumors from NeuT/ATTAC+AP mice.

NIAID Data Ecosystem60

Table_2_Proportional Tumor Infiltration of T Cells via Circulation Duplicates the T Cell Receptor Repertoire in a Bilateral Tumor Mouse Model.xlsx

肿瘤免疫学

T细胞受体库

Temporal analysis of the T cell receptor (TCR) repertoire has been used to monitor treatment-induced changes in antigen-specific T cells in patients with cancer. However, the lack of experimental mode

NIAID Data Ecosystem50

NOTCH1 Drives Sexually Dimorphic Immune Responses in Hepatocellular Carcinoma

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