Cell line data generated for liquidCNA detailed in https://doi.org/10.1101/2021.01.05.425414

LiquidCNA is a novel a method to track subclonal evolution from longitudinally collected cfDNA samples based on somatic copy number alterations. LiquidCNA utilises copy number profiles derived through cost-effective low-pass whole genome sequencing (lpWGS) to automatically and simultaneously genotype and quantify the size of the dominant emerging subclone.Here we generated and sequenced in vitro mixtures of two high-grade serous ovarian cancer cell-lines containing varying proportions of the two cell lines and blood from healthy volunteers. The lpWGS data is used to evaluate the accuracy of liquidCNA.