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p53 gene mutation: software and database.
A large number of different mutations in the tumor suppressor gene p53 gene have been identified in all types of cancer. As of September 1995, this database contains over 4200 mutations. This substant
PubMed Central1996-01-01 更新70
Experiments in concept modeling for radiographic image reports.
OBJECTIVE: Development of methods for building concept models to support structured data entry and image retrieval in chest radiography. DESIGN: An organizing model for chest-radiographic reporting wa
PubMed Central30
A functional assay in Escherichia coli to detect non-assisted interaction between galactose repressor dimers
Among the Escherichia coli operons repressed from multiple sites on DNA, the galactose operon is unique: its repression requires an auxiliary protein, HU, to assist cooperative repressor binding to tw
PubMed Central2000-09-15 更新20
CHRK1, a Chitinase-Related Receptor-Like Kinase in Tobacco
A cDNA encoding a chitinase-related receptor-like kinase, designated CHRK1, was isolated from tobacco (Nicotiana tabacum). The C-terminal kinase domain (KD) of CHRK1 contained all of the conserved ami
PubMed Central40
Structure of the hydrogen bonding complex of O6-methylguanine with cytosine and thymine during DNA replication.
During DNA replication, mutations occur when an incorrect dNTP is incorporated opposite a carcinogen-modified nucleotide. We have probed the structures of the interaction between O 6-methylguanine ( O
PubMed Central1997-08-15 更新30
