Azithromycin resistance evolution in Neisseria gonorrhoeae
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https://www.ncbi.nlm.nih.gov/sra/SRP285072
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资源简介：
The prevalence of azithromycin resistance in Neisseria gonorrhoeae is increasing in a number of populations worldwide. To characterize the genetic pathways leading to high-level azithromycin resistance, a customized morbidostat was used to subject two N. gonorrhoeae reference strains (WHO-F and WHO-X) to dynamically sustained azithromycin pressure. Within 26 days, all cultures evolved high-level azithromycin resistance. We tracked stepwise evolution of resistance by whole genome sequencing.
创建时间：
2021-09-18
