five

Supplemental Material for Milano et al., 2019

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https://figshare.com/articles/dataset/Supplemental_Material_for_Milano_et_al_2019/7934312
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MSH4/MSH5 are critical components of the class I crossover (CO) machinery, which is responsible for >90% of the COs that arise in mammalian meiosis. We generated a point mutation in the ATP binding motif of Msh5, and found that mutant spermatocytes lose all COs, not just those arising from the class I pathway.
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2019-04-03
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