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CoCas9, a compact nuclease from the human microbiome for efficient and precise genome editing

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP495459
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资源简介:
Characterization of the small Cas9 nuclease CoCas9 from Collinsella sp. AM34-10. The PAM sequence of CoCas9 was determined through in vitro cleavage of a synthetic DNA oligonucleotide library. Activity of CoCas9 in the mouse retina was determined by deep sequencing. Precision of CoCas9 was assessed by GUIDE-seq together with SpCas9 and SaCas9.
创建时间:
2024-03-16
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