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Liver X receptor controls a bifurcated transcriptional program where lipogenesis genes overshoot upon refeeding while cholesterol biosynthesis genes return to pre-fasting levels

NIAID Data Ecosystem2026-05-02 收录

脂质代谢调控

甾醇生物合成

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE243057 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-07-11

脂质代谢调控

营养基因组学

Purpose: To investigate the effects of phytosterols intake on systematic and tissue specific lipid metabolism in C57BL/6J mice. Methods: Healthy male C57BL/6J mice were randomly divided into control d

NIAID Data Ecosystem90

Essential role of small bowel microbiota in regulating host digestive and absorptive adaptive responses to dietary lipids

消化道微生物组

脂质代谢调控

Because germ-free (GF) mice are resistant to diet-induced obesity and malabsorb fat, we examined whether small bowel microbiota directly modulate host processes involved in lipid digestion and absorpt

NIAID Data Ecosystem70

RNA-seq investigation of overexpression and knockdown of SCD expression in goose granulosa cells

卵泡发育

脂质代谢调控

Recently, the role of stearoyl-CoA desaturase (SCD) as a regulator of fatty acid desaturation in goose GCs was identified, whereby metabolite changes in lipid-related metabolism, was found to be close

NIAID Data Ecosystem30

Additional file 15 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

表观基因组关联研究

脂质代谢调控

Additional file 15: Table S11. Results of the associations between CpG sites and expression of transcripts of genes codifying for enzymes or proteins directly involved with lipoprotein metabolism. Res

NIAID Data Ecosystem70

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

细胞内吞运输

脂质代谢调控

Supplemental data for Figure 4B. HeLa cells were transfected with siORP5 for 54 h. Cells then received LDL (50 μg/ml) in cholesterol-depleted medium for 18 h followed by processing for filipin stainin

NIAID Data Ecosystem30

Liver X receptor controls a bifurcated transcriptional program where lipogenesis genes overshoot upon refeeding while cholesterol biosynthesis genes return to pre-fasting levels

资源简介：

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