Next generation sequencing facilitates quantitative analysis of MTAC-P (EGFR-TKI resistant cell line derived from PC9) with and without BCAT1 knockdown.

The goals of this study are to compare the different transcriptome signiture between MTAC-P cells with and without BCAT1 knockdown with NGS-derived retinal transcriptome profiling (RNA-seq). Total mRNA profiles of MTAC-P cells with and without BCAT1 knockdown were generated by deep sequencing, in triplicate, using Illumina GAIIx.