Lick1 QTL candidate gene evidence table.

Mean = Mean expression in the Hippocampus Consortium M430v2 (Jun06) PDNN; R MPI = Pearson correlation between probe set and MPI (record 12297); Partial R MPI = Partial Pearson correlation between probe set and MPI (record 12297) when controlling for marker rs13476241; Partial P MPI = P-value of partial correlation. The additive effect shows the contribution of genotype on average log2 expression. A negative or positive additive effect indicates that the B6 or D2 allele increases trait values, respectively. Probe sets 14348893_at, 1427465_at, and 1452308_a_at have multiple probes that overlap B6 vs. D2 sequence variants and show higher expression associated with the B allele which is indicative of a probe artifact (see [78]). However, the use of partial correlation here corrects for these artifacts and any residual covariation is the result of true biological networks. For example, notice the sign change before and after control for these three probe sets to match the sign of the Partial RMPI for the remaining two Atp1a2 probe sets not affected by probe artifacts.