We have transfected a new tumor suppresor gene named ARLTS1 in A549 lung cancer cell line that shows a very low expression level in comparison with normal lung. This line was transfected using the pMV

NIAID Data Ecosystem50

Broad H3K4me3 Reveals Increased Transcription Elongation and Enhancer Activity at Tumor Suppressors. Homo sapiens

肿瘤表观遗传学

肿瘤抑制基因

Tumor suppressors are mostly defined by inactivating somatic mutations in tumors, yet little is known about their epigenetic features in normal cells. Here, through integrative analysis of 1,134 genom

NIAID Data Ecosystem40

The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer

三阴性乳腺癌分子机制

非编码RNA靶点

The development of triple-negative breast cancer (TNBC) is critically regulated by certain tumor-microenvironment-associated cells called mesenchymal stem/stromal cells (MSCs), which we and others hav

NIAID Data Ecosystem60

Cross-validated CE for DiffMut and LOTUS prediction of disease specific TSGs in the single- and multitask settings.

肿瘤抑制基因

多任务学习

Cross-validated CE for DiffMut and LOTUS prediction of disease specific TSGs in the single- and multitask settings.

NIAID Data Ecosystem40